FluoroBeads T Lymphocyte Immunomagnetic Beads

FluoroBeads T Lymphocyte reagents are specialized immunomagnetic beads used for the rapid isolation of T lymphocytes from whole blood or buffy coat samples. Manufactured by One Lambda (a Thermo Fisher Scientific brand), these beads are primarily utilized in HLA (Human Leukocyte Antigen) typing and microlymphocytotoxicity assays.

Key Product Features

• Composition: Superparamagnetic particles coupled with monoclonal antibodies specific to T cells, specifically targeting the CD2+ surface antigen.
• Performance: They can isolate more than 90% of CD2+ T cells from 1 ml of whole blood, typically yielding a lymphocyte population with over 90% purity.
• Efficiency: The isolation process is designed to be completed in less than 10 minutes.
• Regulatory Status: Classified for In Vitro Diagnostic (IVD) use. 

Related Applications

• HLA Typing: Used to prepare pure cell populations for serological HLA Class I typing assays.
• Microcytotoxicity Assays: Isolated cells are reacted with anti-HLA sera and lysed under standard conditions to determine antigen expression.
• Clinical Research: Utilized in studies to determine absolute counts of T lymphocyte subsets (CD3+, CD4+, CD8+) in various medical conditions, such as monitoring patients with squamous cell carcinoma.

Related Components

• FluoroBeads T Developer: A reagent specifically designed to enhance the performance and recovery of cells when using the T lymphocyte isolation method.
• FluoroQuench: Often used in conjunction with FluoroBeads to stain lymphocytes and quench background fluorescence for better visualization under a microscope.
• Anti-T Lymphocyte Control: A monoclonal antibody used to verify the purity of isolated cell populations by checking for T-cell contamination in other suspensions (like B-cell isolations). 

Estimated Pricing in Europe

Based on 2026 market data for similar HLA-specific immunomagnetic isolation kits in the European Union:

• FB1-100 (100 Isolations): Typically ranges between €450 – €650, depending on the country and institutional contract.
• FB1-25 (25 Isolations): Generally estimated at €160 – €220.
• FluoroBeads T Developer (FB1-DEV): Often priced between €100 – €150 as a supplementary reagent. 

Where to Buy in Europe

To obtain a formal 2026 price list or quote, contact these authorized European representatives or distributors:

• Manufacturer’s European Rep: MDSS GmbH in Hannover, Germany, serves as the authorized representative for One Lambda products in the European Community.
• Austria/Eastern Europe: Szabo-Scandic is a primary distributor for these reagents in the DACH region and surrounding areas.
• Italy: Lagitre provides pricing and local support for One Lambda serology and HLA testing products.
• Benelux: Laborimpex often handles specialized lab consumables in Belgium, Luxembourg, and the Netherlands. 

Key Purchase Information

• Regulatory Status: These are CE-IVD marked in Europe, meaning they are approved for clinical diagnostic use in histocompatibility and organ transplantation labs.
• Shipping: These products require cold chain shipping (2° to 8°C), which typically adds a flat refrigerated freight fee (approx. €50–€100) to the order.